e-ISSN: 2717-7149
  • Home
  • About The Journal
  • Editorial Board
  • Instructions for Authors
  • Contact
Current Issue
Ahead Of Print
Archive
Search
Most Popular
Download Articles Read Articles
Retina Arter Tıkanıklıkları ve Tedavisi...
Santral Retinal Ven Tıkanıklığı Güncel Tedavisi...
Central Retinal Artery Occlusion As the Cause of Unilateral Concentric Narrowing of Visual Field and Presence of Cilioretinal Artery...
Bilateral Optic Disc Drusen
Vascular Endothelial Growth Factor and Anti VEGF Agents...
Central Retinal Artery Occlusion As the Cause of Unilateral Concentric Narrowing of Visual Field and Presence of Cilioretinal Artery...
Retina Arter Tıkanıklıkları ve Tedavisi...
Morning Glory Syndrome Associated with Retinochoroidal Coloboma...
Santral Retinal Ven Tıkanıklığı Güncel Tedavisi...
Bilateral Optic Disc Drusen
PureSee Kesintisiz Yüksek Kalitede Görüş
Retina-Vitreous 2012 , Vol 20 , Num 1
Turkish Abstract Abstract Article PDF Similar Articles Mail to Author
Plasma and Vitreous Homocysteine Levels in Type 2 Diabetic Patients with Proliferative Retinopathy
Erdinç AYDIN1, Şemsettin ŞAHİN2
1M.D. Associate Professor, OSM Ortadoğu Hospital, Eye Clinic, Şanlıurfa/TURKEY
2M.D. Associate Professor, Gaziosmanpaşa University Faculty of Medicine, Department of Ophthalmology, Tokat/TURKEY
Purpose: To investigate comparatively plasma and vitreous homosistein (Hcy) levels between the patients with proliferative diabetic retinopathy and the patients with nonproliferative ocular disease.
Material and Methods: Plasma and vitreous samples were obtained simultaneously at the time of vitreoretinal surgery from 16 type 2 diabetic patients with proliferative retinopathy and 13 nondiabetic patients with nonproliferative ocular diseases. Hcy levels were determined by high-performance liquid chromatography.
Results: The vitreous and plasma Hcy concentrations for the diabetic group were (median;range) 1.4 mol/L (0.25-4.3) and 19.55 mol/L (1.8-39.8), respectively. The vitreous and plasma Hcy concentrations for the control group were (median; range) 1.8 mol/L (0.1-3) and 4 mol/L (2-17.2), respectively. Plasma Hcy concentrations for the diabetic group were significantly higher than those for the control group (p=0.004). A remarkable positive correlation between vitreous and plasma Hcy concentrations was present only for the diabetic group (Spearman's, rho=0.487; p=0.056).
Conclusion: Plasma Hcy levels in the patients with PDR were higher than control group. There was no difference of Hcy levels between diabetic and control groups probably due to no severe breakdown of the blood-retina barrier.
Keywords : Diabetic retinopathy, homosistein, plasma, vitreous
PureSee Kesintisiz Yüksek Kalitede Görüş
Home
About The Journal
Editorial Board
Instructions for Authors
Contact