Retina-Vitreous
2012 , Vol 20 , Num 3
Comparison of Posterior Subtenon and Intravitreal Triamcinolone Acetonide Injection on Intraocular Pressure and Lens in the Treatment of Uveitis
1M.D., Aksaray State Hospital, Eye Clinic, Aksaray/TURKEY2M.D. Associate Professor, Numune Training and Research Hospital, Eye Clinic, Ankara/TURKEY Purpose: The aim of this study is to observe and compare effects of 4 mg/0.1 ml intravitreal and 20 mg/0.5 ml subtenon triamcinolone acetonide treatment to intraocular pressure (IOP) and lens, applied for inflammation caused by posterior and intermediate uveitis with different etiologies.
Materials And Methods: The records for 86 eyes of 69 patients being treated for posterior and intermediate uveitis were evaluated on this retrospective study. 42 patients were treated with intravitreal (IVTA) and 44 patients treated with subtenon triamcinolone (PSTA). Clinic follow-up observations were made on 4 control periods; first control period was 1 day, second control period was 1 month, third control period was 3 months and fourth control period was 6 months after injection. During control examinations, intraocular pressures were measured with applanation tonometer and complications for increased lens densities were recorded.
Results: Average intraocular eye pressure levels for intravitreal and posterior subtenon patients were measured as 14.12±1.53 and 14.43±1.85 respectively first day after injection, 23.71±5.20 and 18,41±4.05 at the end of first month after injection, 15.57±2.99 and 15.29±2.31 at the end of third month after injection and 15.05±2,06 and 15.30±2.31 at the end of sixth month after injection. When the results were compared at the end of first month, significant difference between the groups was observed (p<0.05). IOP was clearly increased on IVTA group. However IOP increase on following examinations were not significantly different (p>0.05). Cataract progression or existing opacity increase after IVTA and PSTA injections were observed as 9 (21.4%) on IVTA group and 8 (18.2%) on PSTA group and the difference was not significant (p>0.05).
Conclusion: Although intraocular pressure at the end of first month was higher on IVTA group, no difference was observed on later examinations. Keywords :
