2M.D., Asistant, Dicle University Faculty of Medicine, Department of Ophthalmology, Diyarbakır/TURKEY
3M.D., Professor, Dicle University Faculty of Medicine, Department of Ophthalmology, Diyarbakır/TURKEY Purpose: To evaluate the effectiveness and the results of photodynamic therapy (PDT) with half the dose verteporfin in chronic central serous chorioretinopathy (CSCR).
Materials and Methods: Nineteen eyes of 19 patients diagnosed with chronic CSCR were included in the study. The diagnoses were made by fundus fluorescein angiography and optical coherence tomography (OCT). Corrected logMAR visual acuity (VA) and central macular thickness (CMT) were analyzed before and after treatment. The baseline and the sixth month results were compared.
Results: The mean age of the patients was 37.4±6.1 and 16 (84.2%) of them were male, 3 (15.8%) of them were female. The mean follow-up time was 7.9±2.2 (6-12) months. After PDT, 15 (78.9%) of cases gained minimum one line increase in VA. In three (15.8%) patients visual acuity remained unchanged and in a patient (5.3%) VA decreased one line. There was a significant reduction (p = 0,001) in the mean CMT values when compared before and after PDT. Subretinal fluid in OCT resolved completely in 17 (89.4%) patients and partially in one (5.3%) patients but it showed an increase only in one patient (5.3%). There was not any complication due to PDT in any patients.
Conclusion: Photodynamic therapy with a half the dose verteporfin was considered as an effective treatment in the patients with chronic CSCR.
Keywords : Central serous chorioretinopathy, photodynamic therapy, verteporfin