2Medikal Park Hastanesi, Ankara - TÜRKİYE
3Marmaris Askeri Hastanesi, Marmaris - TÜRKİYE
4Hacettepe Üniversitesi, Ankara - TÜRKİYE Aim: This study was designed to investigate whether the structure and electrical potential of the central retina in subjects with red-green color vision deficiency (RG-CVD) differ from normals, or not.
Methods: Thirty-four male adults with RG-CVD and 34 age-matched male trichromat controls were enrolled. They had full vision and no systemic and ocular diasase except refractive errors within ±3 diopters. In addition to complete ophthalmic exam, they underwent central foveal thickness (CFT) and retinal nerve fiber layer (RNFL, overall global and 4 quadrants) thickness measurements by optical coherence tomography (OCT, Spectralis®, Heidelberg), and multifocal electroretinography (mf-ERG, Retiscan®, Roland). Results in the groups were compared. Five chronic smokers were excluded from the RG-CVD group.
Results: The mean age was 21.51±2.30 years in RG-GVD group and 22.17±2 in controls (p=0.248). CFT and RNFL measurements were similar in both eyes of subjects in both groups (p>0.05 for all). Remarkably, though not all were statistically significant, amplitudes of both N1 and P1 were higher and latencies of both N1 and P1 were shorter in all hexagons in RG-CVD cases, except for the lower P1 and N1 amplitudes found in the most peripheral one.
Conclusion: Subjects with RG-CVD seem to have normal microstructure, but higher electrical potentials with faster activity in the central retina.
Keywords : color vision defi ciency; macula; multifocal electroretinography; optical coherence tomography