2Yrd. Doç. Dr., Ahi Evran Üniversitesi Tıp Fakültesi, Biyokimya Ana Bilim Dalı, Kırşehir, Türkiye Purpose: We aimed to compare serum endocan levels in branch retinal vein occlusion (BRVO) patients and control subjects.
Material and Methods: This study was conducted on 33 BRVO patients and 32 control subjects as a cross-sectional case control study. Serum endocan levels were measured using an enzyme-linked immunosorbent assay.
Results: The mean age, gender distribution and body mass index were similar in the two groups with no significant difference (p>0.05). Serum endocan levels were 34.11±11.33 ng/mL in the BRVO patients and 32.34±8.86 ng/mL in the control group (p=0.487).
Conclusions: Increased serum endocan levels were found in BRVO patients comparing controls subjects, however, the difference was not statistically significant. Further studies evaluating vitreous and/or humor aqueous endocan levels are needed to clarify the pathophysiological role of endocan in BRVO pathogenesis.
Keywords : Endocan, ischemia, neovascularization, branch retinal vein occlusion, vascular endothelial growth factor