2Doç. Dr., Bilim Üniversitesi, Göz Hastalıkları ABD, İstanbul, Türkiye
3Prof. Dr., Bilim Üniversitesi, Göz Hastalıkları ABD, İstanbul, Türkiye Purpose : To evaluate the thickness of retinal nerve fi ber layer (RNFL) in diabetic and hypertensive patients using spectral-fi eld optical coherence tomography (SD-OCT).
Methods : In this study, 30 eyes of 15 patients without diabetic retinopathy and 28 eyes of hypertension without hypertensive retinopathy were included. Twenty-two eyes of 11 patients who were referred to our clinic with refractive complaints as control group were evaluated. OCT was performed for the RNFL thickness in both eyes of all patients and the control group.
Results : The mean RNFL thickness measured in both eyes was 89.09 ± 11 ?m in diabetic patients and 104.52 ± 11 ?m in healthy controls. The mean RNFL thickness measured in both eyes was 90 ± 13 ?m in hypertensive group. When the diabetic group was compared with the control group, the thinning of the RNFL (p-value = 0.002) was observed in the superior and inferior area around the optic disc. Hypertension and RNFL thinning correlation was lower than the diabetic group (p-value = 0.04).
Conclusions : In this study, decreased RNFL in diabetic patients compared to the control group suggests that neurodegeneration is an important component in the early stage of diabetic retinopathy. There was no signifi cant change in hypertension on RNFL.
Keywords : Diabetic retipathy, Hypertension, Neorodegeneration, RNLF thinning, Optic coherence tomography