2Assistant Prof. MD., Selcuk University Medical School, Ophthalmology Department, Konya, Turkey DOI : 10.37845/ret.vit.2020.29.8 Purpose: The aim of this study is to compare superficial flow density (SFD), deep flow density (DFD), choriocapillaris flow density (CFD), superfi cial foveal avascular zone (SFAZ), deep foveal avascular zone (DFAZ), superfi cial vessel density (SVD) and deep vessel density (DVD) of advanced stage pre-proliferative Diabetic Retinopathy patients (PPDR) and normal subjects using optical coherence tomography angiography (OCTA)
Materials and Methods: 40 eyes of 40 advanced stage PPDR patients and 40 eyes of 40 normal subjects were included in this prospective study as study and control groups respectively. Each subject underwent a comprehensive ophthalmic assessment, and OCTA image was taken. The right eye of each participant was used in the study.
Results: There were no significant differences between the study and control groups in respect of age and gender (p>0,05) (Table 1). The mean SFD, DFD, CFD, SFAZ, DFAZ, SVD and DVD values were 1230.92±111.56 mm2, 1185.33±156.15 mm2, 1860.6±56.17 mm2, 0.487±0.205 mm2, 0.646±0.240 mm2, % 47.50±3.15, % 52.38±3.54 in the diabetic group and 1520.22±38.31 mm2, 1596.25±79.83 mm2, 1962.7±26.96 mm2, 0.283±0.057 mm2, 0.340±0.054 mm2, % 54.23±3.27, % 60.72±3.39 in the control group, respectively (Table 1). There were statistically significant differences between the two groups according to SFD, DFD, CFD, SFAZ, DFAZ, SVD and DVD measurements.
Conclusion: Diabetic maculopathy and ischemia can be evaluated with OCTA. As being a rapid and non-invasive procedure, OCTA is particularly helpful in the follow-up and treatment of retinopathy in the early stages, especially in newly diagnosed diabetic patients.
Keywords : Diabetic retinopathy, Optical coherence tomography angiography, Foveal avascular zone, Flow density, Vascular density