2Ophthalmologist, MD, Ankara University Faculty of Medicine, Ankara, Türkiye
3Ophthalmologist, MD, Associate Professor, Ankara University Faculty of Medicine, Ankara, Türk
4Ophthalmologist, MD, Professor, Ankara University Faculty of Medicine, Ankara, Türkiye DOI : 10.37845/ret.vit.2022.31.37 Purpose: To evaluate the structural changes in the choroid by binarization method in intermediate age-related macular degeneration (AMD) and to examine the correlation between parafoveal external retinal and internal retinal thinning.
Material method: Enhanced depth imaging optical coherence tomography images of 50 patients diagnosed with intermediary AMD and age matched 30 healthy subjects were analyzed retrospectively.
Results: Compared to the control group in the AMD group; the central choroidal thickness, choroidal area, stroma area and lumen area were found to be significantly reduced. There was no significant difference in the choroidal vascular index (CVI) compared to the control group in intermediate AMD. In the AMD group, significant thinning was found in the parafoveal inner and outer retinal thickness compared to the control group. When the correlation between parafoveal inner and outer retinal thicknesses and choroidal parameters were evaluated individually in the AMD group, no significant correlation was found.
Discussion: In non-neovascular intermediate AMD cases, there was a decrease in inner and outer retinal thicknesses, central choroidal thickness, lumen and stroma area of the choroid, however, the decrease in CVI was not prominent. No correlation was found to support the hypothesis that inner retinal thinning develops due to choroidal and/or outer retinal changes.
Keywords : Intermediate age related macular degeneration, enhance dept optical coherence tomography, binarization, choroidal vascular index