Turkish Abstract Abstract Free Full Text English Similar Articles Mail to Author

University of Health Sciences, Ankara Etlik City Hospital, Department of Ophthalmology, Ankara, Türkiye DOI : 10.37845/ret.vit.2025.34.11 Sub-internal limiting membrane (sub-ILM) hemorrhage is relatively uncommon and associated with various etiologies. It often results in significant visual impairment due to its tendency to affect the macular region. We present the case of a patient diagnosed with hairy cell leukemia undergoing cladribine treatment, who experienced sudden vision loss due to dense sub-ILM hemorrhage in the macular region, confirmed by optical coherence tomography (OCT), and associated with concurrent anemia and thrombocytopenia. Due to the patient?s leukopenic condition, he was treated with pneumatic tamponade with 100% octafluoropropane (C3F8) gas and prone positioning to facilitate faster visual recovery by displacing the hemorrhage from the fovea. Although the sub-ILM hemorrhage was completely resolved, a macular hole appearance was detected on fundus examination, confirmed by OCT as Stage 1B occult macular hole. The aim of this report is to highlight occult macular hole formation after sub-ILM hemorrhage and discuss the underlying mechanisms proposed as causes of macular hole development after sub-ILM hemorrhage. Keywords : Leukemic retinopathy, macular hole, pneumatic displacement, sub-internal limiting membrane hemorrhage