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Süleyman Demirel Üniversitesi Tıp Fakültesi Göz Hastalıkları A.D., Isparta Purpose: To determine the effect of intravitreal triamcinolone treatment (ITT) on central retinal sensitivity in clinicly significant macular edema (CSME) in diabetic patients.
Material and method: Fifteen eyes with CSME, although previously having at least two session of argon laser photocoagulation treatment (LPT) were included in the study. ITT (4 mg) was applied at least 6 months after following the last LPT. Computerized visual field (HFA 740) (Central 30-2 and macular) threshold tests, visual acuity (VA), intra ocular pressure. (IOP) and biomicroscopic, and funduscopic examinations were performed before and after (1st,3rd- and 6th months) ITT.
Results: Following the ITT (1st, 3rd and 6th months respectively); VA increased in 87 % (13/15 eyes), 73 % (11/15), and 40% (6/15) of the cases. High IOP (>21mmHg) was observed in 27 % (4/15), 13% (2/15), 7% (1/15) of the cases. Improvement in C 30-2 test was observed in 47% (7/15), 33 % (5/15), and 40% (6/15) of the cases. Improvement in Macular threshold test was observed in 20% (3/15), 27% (4/15), and 20 % (3/15) of the cases and worsening of cataract was observed 7% (1/15) of the cases. Intraoperative complication of the ITT was not observed. Postoperatif complications such as retinal detachment, vitreous hemorrhage, endophthalmitis or other complications was not observed during the follow up period.
Conclusion: ITT may be a safe and effective alternative in DME cases that did not respond to Argon LPT but there is still need for the larger series and longer follow up period. Keywords : Triamsinolon, Retinal Sensitivity, Diabetic Macular Edema