Retina-Vitreous
2007 , Vol 15 , Num 2
The Early Results of Posterior Subtenon and Intravitreal Triamcinolone Acetonide Injection for Diffuse Diabetic Macular Edema Treatment
1S.B. Ankara Ulucanlar Göz Eğitim ve Araştırma Hastanesi, Ankara, Uzm. Dr.2S.B. Ankara Göz Eğitim ve Araştırma Hastanesi, Ankara, Uzm. Dr.
3Ankara Ulucanlar Göz Eğitim ve Araş. Hast., Ankara, Asist. Dr.
4Ankara Ulucanlar Göz Eğitim ve Araş. Hast., II.Göz Klinik Şef Yard., Ankara, Doç. Dr.
5Hacettepe Üniversitesi, Tıp Fakültesi, Biyoistatistik, A.D., Ankara, Araş. Gör. Purpose: To evaluate the efficacy of intravitreal and posterior subtenon injection of triamcinolone acetonide (TA) for diffuse diabetic macular edema.
Materials and Methods: Sixteen eyes of 16 patients with diffuse diabetic macular edema were included in this study. Eight of the eyes received 4mg intravitreal injections of TA (group 1 ), while the remaining eight received 40mg posterior subtenon injections of TA (group 2). Visual acuity and intraocular pressure measurements, biomicroscopic anterior segment and fundus examinations were performed during each follow-up visit. The central macular thickness was measured by optical cohorence tomography.before and 1 month after each injection.
Results: The mean age of patients was 56.9±6.9 years (range, 48 to 67 years). The mean duration of diabetes was 15 years. There were no statistically significant difference of central macular thickness between the two groups prior to injections (group 1: 530±105 μm, group 2: 455±98.4 μm, p<0.01). One month after the injections, central macular thickness significantly decreased in both groups (group 1: 334±91.9 μm, group 2: 263±57 μm). Although the decrease was numerically more pronounced in group 2, the difference between the two groups was found statistically insignificant. The visual acuity increase was observed in 50%of the patients and no complications were noted in both groups.
Conclusions: Both intravitreal and posterior subtenon injections of TA were found successful in the treatment of diabetic macular edema, while no statistically significant difference was noted between the efficacy of those two routes of injections. Keywords : Diabetic macular edema, intravitreal triamcinolone acetonide; posterior subtenon triamcinolone acetonide
