Retina-Vitreous
2008 , Vol 16 , Num 4
The Analysis of Optic Disk by OCT in Patients with Retinitis Pigmentosa
1S.B. Ankara Eğitim ve Araştırma Hastanesi 1. Göz Kliniği, Ankara, Op. Dr.2S.B. Ankara Eğitim ve Araştırma Hastanesi 2. Göz Kliniği, Ankara, Op. Dr.
3S.B. Ankara Eğitim ve Araştırma Hastanesi 1. Göz Kliniği, Ankara, Asist. Dr.
4S.B. Ankara Eğitim ve Araştırma Hastanesi 1. Göz Kliniği, Ankara, Doç. Dr.
5S.B. Ankara Eğitim ve Araştırma Hastanesi 2. Göz Kliniği Şef. Yrd., Ankara, Doç. Dr.
6S.B. Ankara Eğitim ve Araştırma Hastanesi 1. Göz Kliniği Klinik Şefi, Ankara, Op. Dr. Purpose: To evaluate peripapillary nerve fiber layer (RNLF) by optical coherence tomography (OCT) in retinitis pigmentosa (RP) patients.
Materials and Methods: Thirty-nine eyes of 39 patients with RP, who admitted to eye clinic between January 2007- January 2008, are included. Best corrected visual acuity and intraocular pressure measurement, biomicroscopic anterior segment and fundus examinations are done to all patients. In addition to the mean RNFL thickness, also RNLF thicknesses in superior, nasal, inferior and temporal quadrants were measured with OCT3 (Zeiss) which was performed by fast RNLF program, circumpapillary in a 3.4 mm diameter. The association of RNFL with sex, age, and visual acuity was evaluated.
Results: The mean age of 21 male (54%) and 18 female (46%) patient was 35.5±12.0 (18-67) year. The mean visual acuity was 0.59±0.51 (0.05-2.10) according to the logMAR units. The intraocular pressure values of all cases were below 21 mmHg. While the mean RNFL thickness of 39 eyes was 87.1±31.7 μm; this mean value was 86.5±37.2 μm in males and 87.8±25.0 μm in females. The superior was detected as the thinnest quadrant and the temporal the thickest quadrant. There was no statistical association between RNLF thickness and sex, age, and visual acuity (p>0.05).
Conclusion: The damage in ganglion cells and the photoreceptors can be determined by the examination of the RNFL in RP with OCT. By this way, the evaluation of the effect of the treatments could become easier. Keywords : Retinitis pigmentosa, optical coherence tomography, retinal nerve fiber layer, ganglion cell
