2Doç. Dr., Haydarpaşa Numune Eğt. ve Arş. Hastanesi, Göz, İstanbul, Türkiye
3Prof. Dr., Haydarpaşa Numune Eğt. ve Arş. Hastanesi, Göz, İstanbul, Türkiye Purpose: To evaluate the infl uence of serous retinal detachment (SRD) on the outcome of intravitreal ranibizumab (IVR) injecton in macular edema due to branch retinal vein occlusion (BRVO).
Material and Methods: Eighteen eyes with cystoid macular edema (CME) and SRD (study group) and 18 eyes with only CME (control group) that received PRN IVR injections during 6 months were evaluated retrospectively. Outcome measures were changes in central macular thickness (CMT) and best corrected visual acuity (BCVA), injection numbers and the the ellipsoid zone (EZ) status.
Results: Mean initial CMT in the study and control groups were 521±119 ?m and 462±98 ?m, respectively. Mean BCVA in the study and control groups were 0.93±0.46 and 0.73 ±0.53 LogMAR, respectively. The baseline CMT and BCVA weren?t signifi cantly different between the groups. The mean injection number was 2.88±0.83 in the study and 1.88±0.96 in the control group during the 6 months (p=0.003). At the last visit, the mean decrease in CMT and the improvement in BCVA wasn?t signifi cantly different between the groups.
Conclusion: The presence of SRD doesn?t seem to effect the IVR therapy in BRVO negatively, conserning the change in CMT and BCVA. Eyes with SRD received more IVR injections compared to eyes with only CME. When whole patients were evaluated disruption of the ellipsoid zone rate was equal in both groups and was correlated with poorer BCVA and increased injection number .
Keywords : Ranibizumab, serous retinal detachment, vein occlusion