Materials and Methods: This prospective study was performed on 70 healthy, young subjects [35 (50%) males and 35 (50%) females] aged between 20 and 30 years who had no history of chronic eye disease and attended the ophthalmology outpatients between March 2012 and August 2012. Only the right eyes of the subjects were included to the study. Macular thickness measurements were performed with the default fast macular thickness scanning mode and PPA mode in random order. All OCT scans were performed by a single experienced physician without pupil dilation within one session. Statistical analyses of fast macular thickness scanning mode and PPA mode differences were performed using the paired samples t-test, the agreement of the measurements was analyzed using the intra-class correlation coefficient (ICC) and the dispersion of the measurements was analyzed using the coefficient of variation (CV).

Results: There was no statistically significant difference between the fast macular thickness scanning mode and PPA mode measurements of all evaluated segments (p values ranged between 0.055 and 0.571). ICC values for these measurements were very high and ranged between 0.984 and 0.992. CV values for the fast macular thickness scanning mode and PPA mode measurements were quite low and ranged between 4.40-5.79% and 4.33-5.76%, respectively.

Conclusion: The fast macular thickness scanning mode and PPA mode measurements using OCT have quite high agreement in healthy, young subjects. Keywords : Macular thickness, optical coherence tomography, posterior pole analysis